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Retinopathy of Prematurity (ROP), also known as retrolental fibroplasia, is a potentially blinding condition affecting the retina of newborns.

In the 1950s it was associated with the use of high amounts of oxygen in neonatal units. Today, modern neonatal care has curbed the incidence, yet because the survival rate of low birth weight infants is much higher, the exposure of surviving babies to required oxygen levels is increasing. The factors that put infants at greatest risk of developing ROP are low birth weight (less than 3.5 pounds) and premature delivery (26-28 weeks).

In babies born prematurely, the growth and development of normal blood vessels in the retina is halted and abnormal vessels may begin to develop. The problem with abnormal vessel growth, known as neovascularization, is that it does not deliver adequate oxygen supply to the retina. In addition, it may cause many secondary problems.

ROP is classified in five stages, depending on the extent of the disease. Progression of the disease to later stages can lead to the formation of scar tissue in the retina and complications such as: retinal detachment, vitreous hemorrhage, strabismus, and amblyopia. Many children with ROP develop nearsightedness.


Because newborns cannot communicate their symptoms, parents, neonatologists, pediatricians and ophthalmologists are keenly aware of risk factors for ROP:

  • Low birth weight (3.5 pounds or less)
  • The need for any oxygen within the first week after birth
  • Unstable health immediately after birth

Children with ROP as infants should be watched for the following symptoms that could signal underlying problems that may not surface until later:

  • Holding objects very close
  • Difficulty seeing distant objects
  • Favouring or winking one eye
  • Reluctance to use one eye
  • Poor vision (previously undetected by the physician)
  • Sudden decrease of vision
  • Crossed or turned eye


For further information, please contact the Research Department on 01 6789004.


Infants at risk for ROP should have an ophthalmic examination at approximately four to six weeks of age. After instilling a series of dilating drops in each eye, the doctor examines the retina with an ophthalmoscope. The exam is often performed while a parent holds the child.

Regardless of whether treatment is required, children should be re-examined at recommended intervals to determine if the progression of the disease has halted, or whether treatment is required.


Some children who develop only stage 1-2 of the disease improve with no treatment. In other cases, treatment is required if it ‘reaches threshold’. This is a term that indicates the presence of stage 3 changes.

To prevent the proliferation of abnormal vascularization, areas of the retina may be frozen with a technique called cryotherapy. Alternatively, laser may be used for the same purpose. Both treatments leave permanent scars in the peripheral retina, but they are often successful in preserving central vision.


For further information, please contact the Research Department on 01 6789004.


Receiving a diagnosis can be overwhelming for anyone, but this is not a journey that you have to make alone. There are many groups and resources available to provide support for people living with Retinopathy of Prematurity.

Fighting Blindness offers a free and confidential counselling service (Insight Counselling). For further information please contact or call 01 6746496.

A mindfulness group is also available on every Wednesday at the Fighting Blindness office at 11am.

For technology support and guidance, the Dublin-based Technology Exchange Club meets every Monday at the Fighting Blindness office at 11am. Another Technology Exchange Club, based in Cork, meet every Saturday in the Cork City Library, Grand Parade, Cork City at 11am. The Cork-based club do not meet on Bank Holiday weekends or on the second Saturday of the month. For further information please contact or call 01 6746496.


Féach provides support for parents of children living with sight loss in Ireland.

ChildVision is the national education centre for children with sight loss in Ireland.

NCBI (National Council for the Blind in Ireland) provides support and services for people living with sight loss in Ireland.

Irish Guide Dogs for the blind helps individuals and their families to achieve improved mobility and independence.