Previous Research Projects

Fighting Blindness supports high-quality, retinal research efforts both in Ireland and abroad. Led by talented and dedicated clinical and scientific teams, their work aims to increase our understanding of the causes and consequences of retinal disease and to ascertain the evidence base towards the development of enhanced clinical care and disease-modifying therapies. Below you can learn more about the previous projects Fighting Blindness has funded.

Elucidation of the role of SARM1 in retinal homeostasis and oxidative stress-induced retinal degeneration.

Dr. Sarah Doyle, Trinity College of Dublin

ORBITAL: Ocular Research By Integrated Training And Learning

Prof. Laurence Fitzhenry, Waterford Institute of Technology 

High-throughput sequencing of inherited and multifactorial macula disease-associated genes and risk factors allows identification of genetic interactions and modifiers.

Prof Frans Cremers, Radboudumc in Nijmegen.

Towards identification of personalised treatments for inherited retinal degenerations by creating patient-specific research models

Prof Brendan Kennedy, University College of Dublin 

A novel formulation for removal of macular oedema

Dr Joanne O’Dwyer, Emerging Researcher Award in 2022, NUI Galway

Cilia-related inherited retinal dystrophy: uncovering fundamental disease mechanism and designing patient-oriented impact
Prof Oliver Blacque and Ms Ailís Moran, University College Dublin

Inherited childhood sight loss: understanding visual cycle biology to develop treatments
Prof Breandán Kennedy and Ms Rebecca Ward, University College Dublin

Pioneering advances for control of myopia in children – The MOSAIC Initiative
Prof James Loughman, Dublin Institute of Technology

Identification of drugs that can safely and effectively maintain visual function in models of inherited retinal degeneration
Prof Breandán Kennedy, University College Dublin

StarT: Innovative Research Training Network focusing on different aspects of Stargardt Disease
Prof Elfride de Baere, University of Ghent, Belgium

Exploring the potential of gene therapy to treat autosomal-dominant retinal disease in a mouse model

Prof. Debra Thompson, University of Michigan, USA

 

Dr. Lucia Celkova

The Target 5000 Programme

Target 5000 logo

Identification And Genotyping Of Patients With Inherited Retinal Disease In Northern Ireland – The Journey

Professor Julie Silvestri, Belfast Health & Social Care Trust, Queen’s University Belfast 

Clinical & Genetic Maternal Study in Leber Hereditary Optic Neuropathy

Professor Lorraine Cassidy, Dr. Clare Quigley and Dr. Kirk Stephenson, Royal Victoria Eye and Ear Hospital, Dublin

Application of next generation sequencing for the genetic characterisation of Irish retinal degeneration patients
Prof Jane Farrar, Trinity College Dublin

Enhancing and expanding the utility of Target 5000

Dr Adrian Dockery and Prof. Jane Farrar

Characterising the IRD population in Northern Ireland through an an all-Ireland retinal degenerations partnership
Ms Giuliana Silvestri, Belfast Health and Social Care Trust, Northern Ireland

Shedding light on unexplained inherited retinal diseases in Ireland and the Netherlands
Prof Frans Cremers, Radbound University, the Netherlands and Prof Jane Farrar, Trinity College Dublin

Clinical Genetics Programme for Inherited Retinal Degenerations

Target 5000 Clinical Fellowships

IRD COUNTS – The impact of living with an inherited retinal degeneration

 

 

Without funding, there is no research.

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