This year our conference will be running on November 3, 4 and 5 at the Radisson Blu Royal Hotel Dublin City.
On Thursday, November 3 our colleagues from the StarT project will present 14 ESR fellows from the StarT network who will present their PhD studies. There will be additional keynote speakers covering the areas of IRD Genomics, Mechanisms of Disease, and Therapeutics. Tickets for the StarT Day are invite-only, however, there is the option to attend the event virtually.
Friday, November 4 is our fantastic Scientific Day and Saturday, November 5 will be our popular Public Engagement Day. While we hope to welcome you personally to our event, we are also aware that an in-person event may not suit everyone. We have virtual tickets available also for those who wish to attend the event online.
Retina 2022 is kindly supported by Abbvie, Roche, Specsavers and Novartis.
Please contact research@fightingblindness.ie or phone +353 1 678 9004 if you require any assistance registering.
09:00 – 9:45 Insights into IRD pathophysiology through disease modelling- patients to cells and zebrafish – Mariya Moosajee, Professor of Molecular Ophthalmology at UCL Institute of Ophthalmology, Group Leader of Ocular Genomics and Therapeutics at the Francis Crick Institute, Consultant Ophthalmologist at Moorfields Eye Hospital and Great Ormond Street Hospital for Children, London, UK.
9:45 – 10:00 Meta-analysis of human retinal transcriptome data – Karla Ruiz
10:00 – 10:15 Interaction map of cis‐regulatory elements controlling ABCA4 in human retina – Soraya Kalayanamontri
10:15 – 10:30 Mapping the cis-regulatory landscape of ABCA4 in adult human retina – Victor Lopez Soriano
10:30 – 10:45 Functional assessment of cis-regulatory elements of ABCA4 and characterization of an abca4 knock-out model in Xenopus tropicalis – Münevver Burcu Cicekdal
10:45 – 11:00 Identification and characterization of a novel retina-specific lncRNA upstream ABCA4 with a potential role in ABCA4-associated inherited retinal disease – Alfredo Dueñas Rey
11:30 – 12:15 Integrating Clinical and Structure/Functional Analysis of the Complex ABCA4 Locus – Rando Allikmets, William and Donna Acquavella Professor at the Departments of Ophthalmology and Pathology & Cell Biology, Director of Research at the Harkness Eye Institute, Columbia University, New York
12:15 -12:30 Phasing at the ABCA4 locus – Ben McClinton
12:30 -12:45 Identification and splice assays of deep-intronic ABCA4 variants in mono-allelic STGD1 – Zelia Corradi
12:45 – 13:00 Using retinal organoids to better understand the pathology of late-onset STGD1 and address the missing heritability in monoallelic cases – Avril Watson
13:00 – 13:15 Antisense oligonucleotide-based splicing modulation therapies for deep-intronic ABCA4 variants in Stargardt Disease – Nuria Suárez Herrera
13:15 – 13:30 Antisense oligonucleotide-mediated treatment of STGD1 caused by variants in ABCA4 – Melita Kaltak
15:00 – 15:45 Gene editing prospects for treating inherited retinal diseases – Alessandra Recchia, PhD, University of Modena and Reggio Emilia, Italy
15:45 – 16:00 Pharmacological rescue of ABCA4 missense variant misfolding and traffic – Davide Piccolo
16:00 – 16:15 AAV-mediated modulation of mitochondrial function in in vitro and in vivo models of Stargardt Disease – Iris Post
16:15 – 16:30 Somatic or germline ABCA4 editing to generate a pig model of Stargardt disease type 1 – Eugenio Pugni
16:30 – 16:45 Effective CRISPR/Cas9-mediated rescue of an ABCA4 splicing defect in photoreceptor precursor cells – Pietro De Angeli
17:00 – 17:10 Closing Presentation – Elfride De Baere
09:15 – 09:30 Welcome Address – Finbarr Roche, CEO, Fighting Blindness
09:30 – 10:00 Complement Therapies in Age-related Macular Degeneration – Professor Catherine Bowes Rickman, Duke University, Durham, NC
10:00 – 10:30 New Views of Retinal Structure and Function in Health and Disease – Professor Austin John Roorda, Herbert Wertheim School of Optometry and Vision Science, University of California, Berkeley, Berkeley CA
10:30 – 10:55 Oral Presentations 1 & 2
10:55 – 11:30 Coffee and Poster Presentations
11:30 – 12:00 Precision Ophthalmology for Stargardt/ABCA4 Disease – Rando Allikmets, William and Donna Acquavella Professor at the Departments of Ophthalmology and Pathology & Cell Biology, and Director of Research at the Harkness Eye Institute, Columbia University, New York
12:00 – 12:30 Gene editing for Inherited Retinal Diseases – Alessandra Recchia, PhD, University of Modena and Reggio Emilia, Italy
12:30 – 12:55 Oral Presentations 3 & 4
12:55 – 13:45 Lunch break
13:45 – 14:30 Poster Presentations
14:30 – 15:00 Dysfunction of the retinal pigment epithelial cells in retinal degeneration – Dr Abigail T. Fahim, MD, PhD, Assistant Professor, Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan
15:00 – 15:30 Eye2Gene: accelerating accurate diagnosis of inherited retinal disease with AI – Dr Nikolas Pontikos, Principal Investigator, UCL Institute of Ophthalmology, Faculty of Brain Sciences, and Moorfields Eye Hospital, UK
15:30 – 16:00 Oral Presentations 5, 6, 7
16:00 – 16:15 Coffee and Poster Presentations
16:15 – 16:45 Clinical Research Update for Inherited Retinal Diseases – Ben Shaberman, Vice President, Science Communications at Foundation Fighting Blindness
16:45 – 16:50 Poster Award
16:50 – 16:55 Geraldine Duggan Early Investigator Award, Sponsored by Novartis
16:55 – 17:10 Summary and closing address
Public Engagement Day 10am – 2pm: Agenda subject to change/additions.
10:00 – 10:30 Welcome: Morning has broken – Visionaries Choir
10:30 – 10:35 Opening Address: We are Fighting Blindness, Finbarr Roche, CEO of Fighting Blindness
10:35 – 10:55 The Fight Goes On. Video address from Michael Griffith
10:55 – 11:15 Life changes – and the most adaptable thrive. Breandan Ward, Xavier Society for the Blind
11:15 – 11:30 Peer Support – The partner’s perspective. Kathryn Sinnott, Fighting Blindness and Clodagh O’Donovan
11:30 – 11:45 Clinical trials must address the patients’ needs. Avril Daly, Retina International
11:45 – 12:15 Break
12:15 – 12:35 Panel discussion, Dr Ellen Moran, Fighting Blindness, joined by Dr Natalie Hudson and Dr Nikolas Pontikos
12:35 – 12:45 Developments in eye health. Video address from Professor David Keegan, Consultant Ophthalmologist, Mater Hospital
12:45 – 13:15 Stay Healthy: Good Eye Health Q&A. Dr. Emma Duignan, Consultant Ophthalmologist, The Royal Victoria Eye & Ear Hospital
13:15 – 13:25 Trinity College Dublin and Fighting Blindness: The story so far. Video presentation
13:25 – 13:55 The treatments currently being developed in eye care. Ben Shaberman, Foundation Fighting Blindness, USA
13:55 – 14:00 The Eric Beggs Award
14:00 – 14:05 Paddy Byrne Empowerment Award. Supported by Novartis
14:05 – 14:15 Closing Address. Finbarr Roche, CEO of Fighting Blindness
Retina 2022 is kindly supported by Novartis, Roche, AbbVie and Specsavers.
Please contact research@fightingblindness.ie or phone +353 1 678 9004 if you require any assistance registering.